In the near future, the earth is covered with yellow sand, and basic crops such as wheat, okra and so on have died out due to wilt. Instead of looking at the stars and indulging in imagination and inspiration as before, human beings count down the few scenes left under the ravages of sandstorms every day. Cooper (Matthew McConaughey), a former NASA astronaut who worked as a domestic farmer, found strange gravity field phenomena in the study of his daughter Murphy (Mackenzie Foy) one after another, and then learned that the former NASA members were still secretly carrying out a plan to save mankind in an unknown area. Many years ago, a mysterious wormhole appeared near Saturn. NASA took the opportunity to send several astronauts to distant galaxies to find habitable planets. Under the persuasion of Professor Brand (Michael Caine), Cooper said goodbye to his daughter painfully, and took a spaceship with the daughters of three other experts and professors, Emilia Brand (Anne Hathaway), Romili (David Gyasi), and Doyle (Wes Bentley), to the three most promising planets currently known. Through the distant galaxy Galaxy, they experienced the vicissitudes of one hour and seven years, and saw the grandeur and mystery of unknown stars and black holes. In the desperate and lonely corner of the vast universe, there is always a steadfast feeling that transcends time and space that connects them closely

近未來的地球黃沙遍野，小麥、秋葵等基礎農作物相繼因枯萎病滅絕，人類不再像從前那樣仰望星空，放縱想像力和靈感的迸發，而是每日在沙塵暴的肆虐下倒數著所剩不多的光景。 在家務農的前NASA太空人庫珀（馬修·麥康納Matthew McConaughey飾）接連在女兒墨菲（麥肯吉·弗依Mackenzie Foy飾）的書房發現奇怪的重力場現象，隨即得知在某個未知區域內前NASA成員仍秘密進行一個拯救人類的計畫。 多年以前土星附近出現神秘蟲洞，NASA借機將數名太空人派遣到遙遠的星系尋找適合居住的星球。 在布蘭德教授（邁克爾·凱恩Michael Caine飾）的勸說下，庫珀忍痛告別了女兒，和其他三名專家教授女兒艾米莉亞·布蘭德（安妮·海瑟薇Anne Hathaway飾）、羅米利（大衛·吉雅西David Gyasi飾）、多伊爾（韋斯·本特利Wes Bentley飾）搭乘太空梭前往現時已知的最有希望的三顆星球考察。 他們穿越遙遠的星系銀河，感受了一小時七年光陰的滄海桑田，窺見了未知星球和黑洞的壯偉與神秘。 在浩瀚宇宙的絕望而孤獨角落，總有一份超越了時空的篤定情懷將他們緊緊相連……